Z701017
Sigma
Burger’s Medicinal Chemistry and Drug Discovery® 6th ed.,Volume 1: Drug Discovery
| ISBN-10: | 0-471-27090-3 |
| ISBN-13: | 978-0-471-27090-4 |
Description
| General description | This edition of Dr. Burger’s classic helps researchers with both traditional and state-of-the-art principles and practices governing new medicinal drug research and development. Completely revised to reflect the many changes that have occurred in the field, it brings together contributions by experts in a wide range of related fields to explore recent advances in the understanding of the structural biology of drug action, as well as cutting-edge technologies for drug discovery. This volume contains new chapters on Virtual Screening, Bioinformatics and Chemical Information Computing Systems in Drug Discovery. |
| Legal Information | Discovery is a registered trademark of Sigma-Aldrich Biotechnology LP and Sigma-Aldrich Co. |
Properties
| publication info | D. Abraham, ed., John Wiley & Sons, 2003, 932 pp., hard cover |
Table Of Contents
| Table of Contents | History of Quantitative Structure-Activity Relationships Recent Trends in Quantitative Structure-Activity Relationships Molecular Modeling in Drug Design Drug-Target Binding Forces: Advances in Force Field Approaches Combinatorial Library Design, Molecular Similarity, and Diversity Applications . Virtual Screening . Docking and Scoring Functions/Virtual Screening Bioinformatics: Its Role in Drug Discovery . Chemical Information Computing Systems in Drug Discovery Structure-Based Drug Design . x-ray Crystallography in Drug Discovery NMR and Drug Discovery Mass Spectrometry and Drug Discovery Electron Cryomicroscopy of Biological Macromolecules Peptidomimetics for Drug Design . Analog Design . Approaches to the Rational Design of Enzyme Inhibitors Chirality and Biological Activity Structural Concepts in the Prediction of the Toxicity of Therapeutical Agents . Natural Products as Leads for New Pharmaceuticals . Index. |
